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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Lysergic acid 3-pentyl amide ： ウィキペディア英語版 Lysergic acid 3-pentyl amide Lysergic acid 3-pentyl amide (3-Pentyllysergamide, LSP) is an analogue of LSD originally researched by David E. Nichols and colleagues at Purdue University. It has similar binding affinity to LSD itself as both a 5-HT1A and 5-HT2A agonist, and produces similar behavioral and physiological responses in animals with only slightly lower potency than LSD. Other isomers of this compound have also been explored, with the 1-pentylamide being around 75% the potency of LSD,〔David E. Nichols. LSD and Its Lysergamide Cousins. ''The Heffter Review of Psychedelic Research''. 2001;2:80-87.〕 while the (R)-2-pentylamide shows similar 5-HT2A binding affinity to LSD ''in vitro'' but has only around half the potency of LSD in producing drug-appropriate responding in mice, and the (S)-2-pentylamide is inactive.〔Monte AP, Marona-Lewicka D, Kanthasamy A, Sanders-Bush E, Nichols DE. Stereoselective LSD-like activity in a series of d-lysergic acid amides of (R)- and (S)-2-aminoalkanes. ''Journal of Medicinal Chemistry''. 1995 Mar 17;38(6):958-66. PMID 7699712〕 ==See also== * Lysergic acid 2-butyl amide * Methylisopropyllysergamide 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Lysergic acid 3-pentyl amide」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.